Structure-Activity Relationships among Zygosporin Derivatives
نویسندگان
چکیده
منابع مشابه
Structure-radical scavenging activity relationships of hydroxytoluene derivatives
Research works proposed that radical scavenging activity of flavonoids is due to ring B, andthe remaining part of the molecule can be disregarded. Thus the objective of this work is toobserve whether hydroxytoluenes account the radical scavenging activity of flavonoid and toestablish structural requirements for their activity (as they showed appreciable activity) andelucidate a comprehensive me...
متن کاملstructure-radical scavenging activity relationships of hydroxytoluene derivatives
research works proposed that radical scavenging activity of flavonoids is due to ring b, andthe remaining part of the molecule can be disregarded. thus the objective of this work is toobserve whether hydroxytoluenes account the radical scavenging activity of flavonoid and toestablish structural requirements for their activity (as they showed appreciable activity) andelucidate a comprehensive me...
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A number of wogonin derivatives have been synthesized as congeners of wogonin and evaluated for their inhibitory activities of PGE2 production. Wogonin derivatives modified at the B ring of wogonin were obtained from 2,4-Dihydroxy-3,6-dimethoxyacetophenone (1) via several steps. Most wogonin derivatives exhibited much reduced inhibitory activities against COX-2 catalyzed PGE2 production compare...
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The depressant effects of phencyclidine [1-(1-phenylcyclohexyl) piperidine, PCP] and three of its analogs (m-amino-PCP, m-nitro-PCP, and PCP-methyliodide) on the spontaneous action potential discharge of cerebellar Purkinje neurons in urethane-anesthetized rats were examined in this study. Both intraperitoneal injection and micro-pressure ejection were employed as routes of drug administration....
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The systematic investigation of purities as antagonists of nucleic acid synthesis in bacteria, viruses, and neoplasms has been under way in these laboratories for a number of years (6, 29, 30, 33, 47, 49). The purines and their analogs have been studied in a wide variety of biological sys tems in an attempt to correlate details of chemical structure with activity. Studies with Lactobacillus cas...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1973
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.21.2268